I like Eaglemode, graphical Emacs (the X kind without GTK), and some of the X window managers as well as mpv. Links (browser) has a graphical mode but it looks much like the curses interface. Worker is an interesting file manager and a good example of a classic X11 program that never died out, but its a bit too orthodox, so I don't use it.
Once you get away from the big GUI silos trying to replicate some other system semi-successfully, you can see the advantages and disadvantages of the Unix-like approach. Unix-likes don't really care much about graphics so there is a lot of complexity in the whole pile of display technologies. Ideally they're just trying to display a TTY, not a graphical environment with GL acceleration and programs capable of displaying OpenGL or Vulkan stuff with specialized hardware and drivers. It took many years for Mesa/drm (not digital rights management) in the kernel/X to work this well for a lot of people, and there are still problems. Desktop software wise, people had to write a lot of standards, XDG/ICCCM/EMWH and so on, and they're not really seamless or without problems, so its kind of terrible for an Apple, Windows, or BeOS clone. But on Unix-likes, you can have it your way usually, you can have your own window manager of choice that works well for you and can be modified to fit your needs, rice Emacs or Vim or whatever, tile those windows, etc.
Oh and NVIDIA doesn't care much about Linux or other open source platforms so CUDA isn't really as relevant (requires proprietary drivers), and OpenCL usage is limited, so there are less programs using or related to that sort of thing.